Celera: Providing Actionable Diagnostic & Genomic Solutions
About UsProduct PipelineResearch & DevelopmentInvestors & MediaCareers
RECENT STUDIES

Celera Diagnostics is conducting disease association studies to identify genetic markers linked to specific diseases for incorporation into new diagnostic products.

Orange Arrow Disease Association Study Methodology

Celera Diagnostics has discovered and replicated a number of novel genetic markers associated with common, complex diseases. Some of the findings which have been recently published or presented include:

Alzheimer's Disease

 
The BDNF val66met polymorphism is not associated with late onset Alzheimer’s disease in three case–control samples -
[ Published in Molecular Psychiatry - June, 2005 ]

Genetic Association of the APP Binding Protein 2 Gene (APBB2) with Late Onset Alzheimer Disease
[ Published in Human Mutation - December, 2004 ]

Breast Cancer

Translating Cancer Markers into Diagnostics Assays - American Association for Cancer Research – Oncogenomics 2005 –
[ Presentation at Oncogenomics 2005 - San Diego, CA - February 2, 2005 ]

Cardiovascular Disease

Association of the Trp719Arg Polymorphism in Kinesin-Like Protein 6 With Myocardial Infarction and Coronary Heart Disease in 2 Prospective Trials: The CARE and WOSCOPS Trials
[ Published in J Am Coll Cardiol - January 2008 ]

A Kinesin Family Member 6 Variant Is Associated With Coronary Heart Disease in the Women’s Health Study
[ Published in J Am Coll Cardiol - January 2008 ]

Polymorphism in KIF6 Gene and Benefit From Statins After Acute Coronary Syndromes: Results From the PROVE IT-TIMI 22 Study
[ Published in J Am Coll Cardiol - January 2008 ]

Evaluation of the Paraoxonases as Candidate Genes for Stroke
[Published in Stroke - October, 2005]

  Identification of Four Gene Variants Associated with Myocardial Infarction
[ Published in The American Journal of Human Genetics - October, 2005 ]

Replicated Association of a Purinergic Receptor Variant With Risk of Myocardial Infarction - March 8, 2005
[ Presentation at American College of Cardiology – Annual Scientific Session 2005 ]

A Polymorphism in the Metabotropic Glutamate Receptor 8 Gene is Strongly Associated with Myocardial Infarction in Two Independent Studies - March 6, 2005
[ Poster from American College of Cardiology – Annual Scientific Session 2005 ]

Replicated Associations of Genetic Variants With Coronary Artery Disease And Myocardial Infarction
A 7,500 Gene Study - March 4, 2005
[ Presentation at American College of Cardiology – Annual Scientific Session 2005 ]

Hepatitis C / Interferon Therapy Response

Association of Fibrosis Risk in HCV Patients with a Missense SNP in Gene CPT1A - 2005
[ Presentation at 40th Annual Meeting of the European Association for the Study of the Liver (EASL) – Paris, France – April 15, 2005 ]

Identification of Novel Genetic Markers Associated with Fibrosis Progression Risk in HCV Patients - 2004
[ Presentation at American Association for the Study of Liver Diseases – Boston - October 29 - November 2, 2004 ]

Gene Expression Profiles of Patients with Chronic Hepatitis C (CH-C) Treated with Pegylated Interferon alfa-2b and Ribovirin (PEG-INF/RBV)
[ Poster presented at Digestive Disease Week – New Orleans, LA - May 15-20, 2004 ]

Rheumatoid Arthritis

  PTPN22 Genetic Variation: Evidence for Multiple Variants Associated with Rheumatoid Arthritis
[ Published in Am. J. Hum. Genet. - October, 2005 ]

Association of the PTPN22 C1858T single-nucleotide polymorphism with rheumatoid arthritis phenotypes in an inception cohort
[ Published in Arthritis and Rheumatism - September, 2005 ]

Arthritis Foundation Names PTPN22 association as one of the Top 10 Arthritis Advances of 2004 - December 2004
[ Read the Arthritis Foundation Top 10 list]

A Missense Single-Nucleotide Polymorphism in a Gene Encoding a Protein Tyrosine Phosphatase (PTPN22) Is Associated with Rheumatoid Arthritis
[ Paper published in American Journal of Human Genetics ]
[ Read NARAC press release ]

Analysis of Families in the Multiple Autoimmune Disease Genetics Consortium (MADGC) Collection
[ Published in Am. J. Hum. Genet. - February, 2005 ]

                                                                                                                                                                                                       

HOME CONTACT SITE MAP SEARCH Submit  
© 2008 Celera. All Rights Reserved.   | Privacy Statement | Terms of Use | Investor Advisories | Prescription Drug Marketing Policy
built@zoomedia