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| RECENT STUDIES | ||||
Celera Diagnostics is conducting disease association studies to identify genetic markers linked to specific diseases for incorporation into new diagnostic products.
Celera Diagnostics has discovered and replicated a number of novel genetic markers associated with common, complex diseases. Some of the findings which have been recently published or presented include: Alzheimer's Disease Genetic Association of the APP Binding Protein 2 Gene (APBB2) with Late Onset Alzheimer Disease
Breast Cancer Translating Cancer Markers into Diagnostics Assays - American Association for Cancer Research – Oncogenomics 2005 – Cardiovascular Disease Association of the Trp719Arg Polymorphism in Kinesin-Like Protein 6 With Myocardial Infarction and Coronary Heart Disease in 2 Prospective Trials: The CARE and WOSCOPS Trials A Kinesin Family Member 6 Variant Is Associated With Coronary Heart Disease in the Women’s Health Study Polymorphism in KIF6 Gene and Benefit From Statins After Acute Coronary Syndromes: Results From the PROVE IT-TIMI 22 Study Evaluation of the Paraoxonases as Candidate Genes for Stroke
Identification of Four Gene Variants Associated with Myocardial Infarction Replicated Association of a Purinergic Receptor Variant With Risk of Myocardial Infarction - March 8, 2005 A Polymorphism in the Metabotropic Glutamate Receptor 8 Gene is Strongly Associated with Myocardial Infarction in Two Independent Studies - March 6, 2005 Replicated Associations of Genetic Variants With Coronary Artery Disease And Myocardial Infarction
Hepatitis C / Interferon Therapy Response Association of Fibrosis Risk in HCV Patients with a Missense SNP in Gene CPT1A - 2005 Identification of Novel Genetic Markers Associated with Fibrosis Progression Risk in HCV Patients - 2004 Gene Expression Profiles of Patients with Chronic Hepatitis C (CH-C) Treated with Pegylated Interferon alfa-2b and Ribovirin (PEG-INF/RBV) Rheumatoid Arthritis
PTPN22 Genetic Variation: Evidence for Multiple Variants Associated with Rheumatoid Arthritis Association of the PTPN22 C1858T single-nucleotide polymorphism with rheumatoid arthritis phenotypes in an inception cohort Arthritis Foundation Names PTPN22 association as one of the Top 10 Arthritis Advances of 2004 - December 2004 A Missense Single-Nucleotide Polymorphism in a Gene Encoding a Protein Tyrosine Phosphatase (PTPN22) Is Associated with Rheumatoid Arthritis Analysis of Families in the Multiple Autoimmune Disease Genetics Consortium (MADGC) Collection
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