L. Bare et al., (2012) Small apo(a) isoforms of Lp(a) are associated with myocardial infarction in a study of Costa Ricans from the Central Valley of Costa Rica.
[ Presentation at Arteriosclerosis, Thrombosis, and Vascular Biology Annual Meeting 2012 - April 2012 ]

J. Devlin et al., (2012) Statin adherence in males and females and the impact of knowledge of a genetic test: Results from the AKROBATS trial.
[ Poster at American Heart Association-Quality of Care and Outcomes 2012 - May 2012 ]

J. Devlin et al., (2012) Patient knowledge of pharmacogenetic information improves adherence to statin therapy: Results of the additional KIF6 risk offers better adherence to statins (AKROBATS) trial.
[ Poster at American College of Cardiology 2012 – March 2012 ]

Y. Li et al., (2012) Stain Personalized.
[ Published in Clinic in North America- January 2012 ]

M Luke et al., (2012) Pilot candidate gene analysis of patients >60 years old with aortic stenosis involving a tricuspid aortic valve.
[ Published in American Journal of Cardiology- May 2012 ]

Bare et al., (2012) Multiple SNP testing improves risk prediction of first venous thrombosis.
[ Published in Blood – May 2012 ]

M. Luke et al., (2011) Polymorphisms and non-cardioembolic stroke in three case-control studies.
[ Published in Cerebrovascular Disease- December 2011 ]

Y. Li et al., (2011) Genetic variants in the KIF6 locus and coronary event reduction from statin therapy.
[ Published in Human Genetics – October 2011 ]

D. Shiffman et al., Genome-wide association analysis of soluble ICAM-1 concentration reveals novel associations at the NFKBIK, PNPLA3, RELA and SH2B3 loci.
[ Published in Plos Genetics- May 2011 ]

Y. Li et al., Two single nucleotide polymorphisms in the apolipoprotein(a) gene are predictors of the risk of coronary heart disease.
[ Poster at NLA 2011 – May 2011 ]

A. Baca et al., Bimodal distribution of Lipoprotein(a) in carriers of the LPA 4399Met allele LPA genotype correlates with increased Lipoprotein(a) levels.
[ Poster at NLA 2011-May 2011 ]

D. Shiffman et al., Cost-effectiveness of genetic testing of LPA variants associated with coronary heart disease.
[ Presentation at 16th World Congress of Cardiology – July 2011 ]

J. Devlin et al., Dietary supplement use in patients enrolled in the additional KIF6 risk offers better adherence to statins (AKROBATS) trial.
[ Published in Journal Clinical Lipidology – June 2011 ]

L. Bare et al., Cost effectiveness of targeted statin therapy following genotype testing among acute coronary syndrome patients.
[ Poster at 16th World Congress of Cardiology – July 2011 ]

D. Shiffman et al., Genome-wide study of gene variants associated with differential event reduction by pravastatin therapy.
[ Poster at 2011 AHA Basic Science Cardiovascular Disease – July 2011 ]

R. Superko et al., Genetic testing for early detection of individuals at risk of coronary heart disease and monitoring response to therapy: Challenges and promises.
[ Published in Current Atherosclerosis Report - August 2011 ]

Y. Li et al., Genetic variants in the Apolipoprotein(a) gene and coronary heart disease.
[ Published in Circulation Cardiovascular Genetics - October 2011 ]

D. Ross et al., Correlation of lipoprotein parameters in a large cardiology prevention community database.
[ Poster at WIRC 2011 – Nov 2011 ]

Li et al., (2010) Genetic variants in the KIF6 region and coronary event reduction from statin therapy
[ Published in Human Genetics - October 2010 ]

Superko et al., (2010) Combination niacin extended-release and simvastatin treatment causes greater reduction in atherogenic particles compared to atorvastatin monotherapy
[ Published in Vascular Health and Risk Management - October 2010 ]

Shiffman et al., (2011) The contribution of a 9p21.3 variant, a KIF6 variant, and C-reactive protein to predicting risk of myocardial infarction in the Cardiovascular Health Study
[ Published in BMC Cardiovascular Disorders - March 2011 ]

Superko., (2011) Survival bias and drug interaction can attenuate cross-sectional case-control comparisons of genes with health outcomes. An example of the kinesin-like protein 6 (KIF6) Trp719Arg polymorphism versus coronary heart disease
[ Published in BMC Cardiovascular Disorders - March 2011 ]

Shiffman et al., (2010) Single variants can explain the association between coronary heart disease and haplotypes in the apolipoprotein(a) locus.
[ Published in Atherosclerosis - September 2010 ]

Bare et al., (2010) Investigation of KIF6 Trp719Arg in a case-control study of myocardial infarction: a Costa Rican population.
[ Published in PlOS One - September 2010 ]

Li Y et al., (2010) KIF6 polymorphism as a predictor of risk of coronary events and of clinical event reduction by statin therapy
[ Published in Am J Cardiol - August 2010 ]

Genetic Marker of CHD Risk and Benefit from Aspirin Therapy
[Dov Shiffman Presentation at New Cardiovascular Horizons - June 2010]

"LPA - Genetic Marker of CHD Risk and Benefit from Aspirin Therapy
[ Dov Shiffman Presentation at PHRI (Salim Yusuf) - June 2010]

A variant of the LPA gene predicts cardiovascular event reduction by aspirin therapy in a primary prevention setting
[ Dov Shiffman NLA Scientific Sessions, Chicago - May 2010]

Simvastatin does not alter the expression of KIF6, a new coronary heart disease risk marker that is expressed by macrophages in atherosclerotic lesions of humans and mice
[ Dov Shiffman Presentation at ATVB Annual Meeting 2010 - April 2010]

Bare et al., (2010) A follow-up study of a genome-wide association scan identifies a susceptibility locus for venous thrombosis on chromosome 6p24.1.
[ Published in AJHG - April 2010 ]

KIF6 variant predicts both increased risk for coronary events and reduction of events from statin therapy
Results from the CARE, WOSCOPS, PROSPER, and PROVE IT studies
[ Presentation at German Cardiac Society- CV Research - April 2010]

Garret-Superko et al., (2010) Genetic and Advanced Coronary Heart Disease Risk Factors Are Under-Diagnosed in Cardiac Rehabilitation Patients.
[ Presented at Preventive Cardiovascular Nurses Association - April 2010 ]

Bare et al., (2010) West African and Amerindian ancestry and risk of myocardial infarction and metabolic syndrome in the Central Valley population of Costa Rica.
[ Presented at Published in Human Genetics] - March 2010 ]

Shiffman et al., (2010) Effect of pravastatin therapy on coronary events in carriers of the KIF6 719Arg allele from the cholesterol and recurrent events trial.
[ Published in Am J Cardiol - March 2010 ]

Superko et al., (2010) Statins in acute coronary syndromes and genetic insight
[ Published in J Am Cardiol Coll - March 2010 ]

Superko et al., (2010) Letter by Superko and King regarding article, "Lipid Treatment Assessment Project 2: a multinational survey to evaluate the proportion of patients achieving low-density lipoprotein cholesterol goals"
[ Published in Circulation - March 2010 ]

Pravastatin Therapy Among All Ethnic Groups of CARE Reduced Primary End Point Events in Carriers of the KIF6 719Arg Allele, but not in Noncarriers
[Presentation at ACC 2010 - March 2010]

Iakoubova et al., (2010) KIF6 Trp719Arg polymorphism and the effect of statin therapy in elderly patients: results from the PROSPER study.
[ Published in European Journal of Cardiovascular Prevention and Rehabilitation - March 2010 ]

Bare et al., (2010) Updated analysis of gene variants associated with deep vein thrombosis.
[ Published in JAMA - February 2010 ]

Li Y et al., (2010) Genetic variants in the KIF6 region and coronary event reduction from statin therapy
[ Published in Human Genetics - 2010 ]

Chasman et al., (2008) Polymorphism in the apolipoprotein(a) gene, plasma lipoprotein(a), cardiovascular disease, and low-dose aspirin therapy.
[ Published in Atherosclerosis - September 2008 ]

Shiffman et al., (2008) Analysis of 17,576 Potentially Functional SNPs in Three Case–Control Studies of Myocardial Infarction.
[ Published in PLoS ONE - August 2008 ]

Iakoubova et al., (2008) Association of the Trp719Arg Polymorphism in Kinesin-Like Protein 6 With Myocardial Infarction and Coronary Heart Disease in 2 Prospective Trials: The CARE and WOSCOPS Trials.
[ Published in J Am Coll Cardiol - January 2008 ]

Shiffman et al., (2008) A Kinesin Family Member 6 Variant Is Associated With Coronary Heart Disease in the Women’s Health Study.
[ Published in J Am Coll Cardiol - January 2008 ]

Iakoubova et al., (2008) Polymorphism in KIF6 Gene and Benefit From Statins After Acute Coronary Syndromes: Results From the PROVE IT-TIMI 22 Study.
[ Published in J Am Coll Cardiol - January 2008 ]

Shiffman et al., (2007) Association of Gene Variants With Incident Myocardial Infarction in the Cardiovascular Health Study.
[ Published in Arteriosclerosis, Thrombosis, and Vascular Biology - November, 2007 ]

Bare et al., (2007) Five common gene variants identify elevated genetic risk for coronary heart disease.
[ Published in Genetics in Medicine - October, 2007 ]

Luke et al., (2007) A Polymorphism in the Protease-Like Domain of Apolipoprotein(a) Is Associated With Severe Coronary Artery Disease.
[ Published in Arteriosclerosis, Thrombosis, and Vascular Biology - June, 2007 ]

Morrison et al., (2007) Prediction of Coronary Heart Disease Risk using a Genetic Risk Score: The Atherosclerosis Risk in Communities Study.
[ Published in American Journal of Epidemiology - April, 2007 ]

Iakoubova et al., (2006) Asp92Asn Polymorphism in the Myeloid IgA Fc Receptor Is Associated With Myocardial Infarction in Two Disparate Populations.
[ Published in Arteriosclerosis, Thrombosis, and Vascular Biology - September, 2006 ]

Shiffman et al., (2006) Gene Variants of VAMP8 and HNRPUL1 Are Associated With Early-Onset Myocardial Infarction.
[ Published in Arteriosclerosis, Thrombosis, and Vascular Biology - July, 2006 ]

Shiffman et al., (2005) Identification of Four Gene Variants Associated with Myocardial Infarction. Am. J. Hum. Genet. 77:596-605.
[ Published in The American Journal of Human Genetics - October, 2005 ]
[ Supplement ]

Replicated Association of a Purinergic Receptor Variant With Risk of Myocardial Infarction - March 8, 2005
[ Presentation at American College of Cardiology – Annual Scientific Session 2005 ]

A Polymorphism in the Metabotropic Glutamate Receptor 8 Gene is Strongly Associated with Myocardial Infarction in Two Independent Studies - March 6, 2005
[ Poster from American College of Cardiology – Annual Scientific Session 2005 ]

Replicated Associations of Genetic Variants With Coronary Artery Disease And Myocardial Infarction
A 7,500 Gene Study - March 4, 2005
[ Presentation at American College of Cardiology – Annual Scientific Session 2005 ]

5th World Stroke Congress - June 25, 2004 - Vancouver, BC
[ Poster .pdf ]

International Vascular Biology Meeting - June 3, 2004 - Toronto, Canada
[ Read press release ]
[ Poster .pdf ]

Novel Genetic Markers Associated with Risk of Myocardial Infarction From a Genomic Scale Scan of Putative Functional Polymorphisms
Poster from the International Vascular Biology Meeting
June 3, 2004 - Toronto, Canada [.pdf]

American College of Cardiology - March 8, 2004 - New Orleans, LA
[ Summary .pdf ]
[ Poster .pdf ]

Novel Genetic Markers Associated with Myocardial Infarction: A Genomic Scale Scan of Putative Functional Polymorphisms
Poster from the American College of Cardiology Meeting
March 8, 2004 - New Orleans, LA [.pdf]

13th International Symposium on Atherosclerosis - September 30, 2003 - Kyoto, Japan
[ Read press release ]

Deep Vein Thrombosis

Genetic Variants Associated With Deep Vein Thrombosis: the F11 Locus
[Published in Journal of Thrombosis and Haemostasis - July, 2009 ]

Gene Variants Associated With Deep Vein Thrombosis
[ Published in JAMA - March, 2008 ]

Stroke

A 4q25 Variant and Cardioembolic Stroke in the Vienna Stroke Registry
[ Presentation at International Stroke Genetics Consortium 2010 - November 2010 ]

A 4q25 Variant and Cardioembolic Stroke in the Vienna Stroke Registry
[ Presentation at International Stroke Genetics Consortium 2010 - July 2010 ]

Luke et al., (2009) Polymorphisms Associated with Both Noncardioembolic Stroke and Coronary Heart Disease: Vienna Stroke Registry.
[ Published in Cerebrovasc Dis - September 2009 ]

Morrison et al., (2008) Single nucleotide polymorphisms associated with coronary heart disease predict incident ischemic stroke in the Atherosclerosis Risk in Communities (ARIC) study.
[ Published in Cerebrovasc Dis - September 2008 ]

Evaluation of the Paraoxonases as Candidate Genes for Stroke
[ Published in Stroke - October, 2005 ]