Celera is conducting disease association studies to identify biomarkers linked to common complex diseases. These biomarkers may be useful in monitoring response to therapy, or in predicting predisposition for disease, disease progression, or response to therapy.

Genotyping studies compare DNA from people with a disease (cases) to DNA from healthy individuals (controls) to identify associations between genetic variations and disease. Novel associations are then confirmed and validated in DNA from prospective studies of the populations similar to those in which a diagnostic test will ultimately be used.

Gene expression and proteomic studies analyze RNA or protein patterns to help characterize a cancer patientís risk for metastasis, to select therapy and monitor response to therapy, to identify patients who may benefit from imaging tests, or to confirm the result of an imaging test prior to biopsy.