Notable Patents

Celera holds numerous United States and foreign patents based on its discoveries. Listed below are United States patents covering notable discoveries in select disease areas:

Coronary Heart Disease:

  • KIF6
    • 7,799,530 - Genetic polymorphisms associated with cardiovascular disorders and drug response, methods of detection and uses thereof
    • 7,695,916 - Genetic polymorphisms associated with cardiovascular disorders and drug response, methods of detection and uses thereof
  • LPA
    • 7,781,168 - Genetic polymorphisms associated with myocardial infarction, methods of detection and uses thereof

Cancer:

  • Breast cancer: 7,695,915 - a molecular prognostic signature for predicting breast cancer metastasis, and uses thereof
  • Lung Cancer: 7,892,760 - Lung cancer markers and uses thereof
  • Cancer targets:
    • Lung: 7,807,392 and 7,521,195 - Lung disease targets and uses thereof
    • Colon: 7,776,555 and 7,842,466 - Colon disease targets and uses thereof
    • Kidney: 7,611,703 and 7,608,413 - Kidney disease targets and uses thereof
    • Pancreatic: 7,473,531 and 7,358,231 - Pancreatic disease targets and uses thereof
    • Breast: 7,842,467 - Breast disease targets and uses thereof

Autoimmune Disease:

  • Rheumatoid Arthritis
    • PTPN22 : 7,833,706 - Genetic polymorphisms associated with rheumatoid arthritis, methods of detection and uses thereof
    • TRIP : 7,811,794 - Genetic polymorphisms associated with rheumatoid arthritis, methods of detection and uses thereof
    • TRAF1 : 7,863,021 - Genetic polymorphisms associated with rheumatoid arthritis, methods of detection and uses thereof

Liver Disease:

    • TLR4 : 7,820,380 - Genetic polymorphisms associated with liver fibrosis in hepatitis c virus-infected subjects, methods of detection and uses thereof
    • AZIN1 : 7,727,725 - Genetic polymorphisms associated with liver fibrosis, methods of detection and uses thereof

Neurodegenerative Disease:

  • DAPK : 7,695,911 - Genetic polymorphisms associated with Alzheimer's disease, methods of detection and uses thereof
  • NEDD9 : 7,816,083 - Genetic polymorphisms associated with neurodegenerative diseases, methods of detection and uses thereof
  • GALP : 7,651,840 - Genetic polymorphisms associated with Alzheimer's disease, methods of detection and uses thereof

Small Molecules:

  • Cathespin K inhibitor (licensed to Merck): 7,375,134 - Cathepsin cysteine protease inhibitors