Breast Cancer

C. Christopherson et at., (2012) Glycolytic gene expression in ER positive breast cancer tumors: comparison with a metastasis score.
[ Poster at American Association Cancer Research 2012- March 2012 ]

C. Christopherson et al., (2011) Profiling the metabolic dependencies of PI3K-mutant cancers.
[ Poster at AACR- NCI- EORTC 2011 November 2011 ]

A. Grupe et al., Breast cancer gene expression signatures- Utility beyond predicting metastatic potential and tamoxifen response.
[ Presentation at 3rd Oncology Biomarkers Conference January 2011 ]

Y. Li et al., Analysis of single nucleotide polymorphisms in case-control studies.
[ Published in Methods Molecular Biology - March 2011 ]

A. Grupe et al., Prognosis and core processes in metastatic breast cancer: Correlation of a composite metastasis score (cMS) and Oncotype Dx recurrence score.
[ Presentation at Biomarker World Congress 2011- May 2011 ]

S. Kwok et al., Differential impact of gefitinib and PLX-4720 on proliferation of MCF10A isogenic cell lines as measured with a metastasis expression score.
[ Poster at SABCS 2011 Dec 2011 ]

Investigation into the influence of the H1047R PIK3CA mutation on the bioenergetic dependency of breast cancer cells
[ Presented at 2011 American Association for Cancer Research, April 2-6 2011, Orlando ]

Sninsky et al., (2010) A multigene predictor of metastatic outcome in early stage hormone receptor-negative and triple-negative breast cancer
[ Published in 2010 Breast Cancer Research - December 2010 ]

Dose-dependent PI3K inhibitor associated decreases of proliferation and glycolytic index expression scores in human breast epitheal isogenic cell lines
[ Poster from SABCS 2010- December 2010 ]

Correlation of a Proliferation Index Combined with Progesterone Receptor to Oncotype DX in Early Stage ER-Positive Breast Cancer
[ Poster from SABCS 2010 - December 2010 ]

Development of an ER-Negative Prognostic Immune Response Score Identified from Microarrays to Multiplex RT-PCR Assays for Fixed Tissue Studies
[ Poster from AMP 2010 - November 2010 ]

Dose-dependent PI3K inhibitor associated decreases of proliferation and glycolytic index expression scores in human breast epitheal isogenic cell lines
[ Poster from ASCO 2010 - October 2010 ]

Sninsky et al., (2010) A multigene predictor of metastatic outcome in early stage hormone receptor-negative and triple-negative breast cancer
[ Published in Breast Cancer Research - October 2010 ]

Molecular insight into metastatic potential and response to tamoxifen in breast cancer
[ Presentation at ADAPT 2010- September 2010 ]

A High Throughput Semi-automated RNA Extraction Method from Formalin-Fixed, Paraffin-Embedded Specimens for mRNA Quantitative Assays of Cancer Biomarkers
[ Poster from AACC 2010 - July 2010 ]

Metastasis Score expression profiling of isogenic cell lines with defined oncogenic mutations and upon treatment with an inhibitor of PI3K/PTEN signaling pathway
[ Poster from Translational Cancer Medicine - July 2010 ]

Composite and Component Expression Score Correlations in ER-Positive Breast Cancer
[ Poster Presentation at ASCO 2010 - June 2010 ]

Risk Partitioning Model Shows Need to Address Time Dependence of Breast Cancer Recurrence
[ Poster from ASCO 2010- June 2010 ]

Molecular Insight into metastatic potential and response to tamoxifen in breast cancer
[ Presentation at 2010 Biomarker World Congress - May 2010 ]

Correlations of Component and Composite Metastasis Scores for Early Stage Breast Cancer
[ Miami Breast Cancer Conference - March 2010 ]

A 14-gene prognosis signature predicts metastasis risk in node-negative, estrogen receptor-positive, Tamoxifen-treated breast cancer in different ethnogeographic regions
[ Presented as a poster at the 26th Annual Miami Breast Cancer Conference (March 4-7, 2009) ]

Ayuko A. Iverson, Cheryl Gillett, Paul Cane, Christopher D. Santini, Thomas M. Vess, Lauren Kam-Morgan, Alice Wang, Marcia Eisenberg, Charles M. Rowland, Janice J. Hessling, Samuel E. Broder, John J. Sninsky, Andrew Tutt, Steven Anderson, and Sheng-Yung P. Chang. A Single-Tube Quantitative Assay for mRNA Levels of Hormonal and Growth Factor Receptors in Breast Cancer Specimens. Published in J Mol Diagn. 2009 Mar;11(2):117-30.
[ Article (March 4-7, 2009) ]

Risk estimation of distant metastasis in node-negative, estrogen receptor-positive breast cancer patients using an RT_PCR based prognostic expression signature
[ BioMed Central - November 21, 2008 ]

Data Validating Its Metastasis Score as a Molecular Prognostic Tool in Breast Cancer
[ Presented as a poster at the 24th annual Miami Breast Cancer Conference in Miami Beach, FL - February 2007 ]

An RT-PCR-based multi-gene prognostic signature predicts distant metastasis of node negative, ER positive breast cancer from FFPE sections.
[ Abstract presented at ASCO 42nd Annual meeting Chicago - June 2006 ]

Translating Cancer Markers into Diagnostics Assays - American Association for Cancer Research Oncogenomics 2005
[ Presentation at Oncogenomics 2005 - San Diego, CA - February 2, 2005 ]

24th Congress of the International Association for Breast Cancer Research - November 3, 2003 - Sacramento, CA
[ Abstract .pdf ]
[ Poster .pdf ]

Colon Cancer

Colorectal Cancer Serum Protein Markers Identified Through Mass Spectrometry-based Proteomic Discovery Programs
Poster from AACR April 15 2009 - Denver, CO [.pdf]

CD133/Prominin-1 Is A Novel Antibody Therapeutic Target in Pancreatic, Gastric and Hepatocellular Cancers
Poster from AACR Annual Meeting, April 15-18, 2007 - Los Angeles, CA [.pdf]

Proteomic analysis of colorectal tumor cells identifies CD133/Prominin-1, a cancer stem cell marker, as a monoclonal antibody therapeutic candidate
Poster from AACR Annual Meeting, April 15-18, 2007 - Los Angeles, CA [.pdf]

Lung Cancer

Mass Spectrometry-Based Identification and Validation of Protein Biomarkers for Detection of Lung Cancer
Poster from AACR Annual Meeting, April 15, 2009 - Denver, CO [.pdf]

Lung cancer biomarkers identified through mass spectrometry-based proteomic discovery from tissue and cell lines
Poster from AACR Annual Meeting, April 15-18, 2007 - Los Angeles, CA [.pdf]

The Use of Mass Spectrometry Based Proteomics to Identify Cell Surface Proteins Applicable for Monitoring Drug Resistance, Response and Therapeutic Targeting
Poster from AACR Annual Meeting, April 15-18, 2007 - Los Angeles, CA [.pdf]

Pancreatic Cancer

Pancreatic Cancer Serum Protein Markers Identified Using Mass-spectrometry Based Discovery Platform
Presentation at the AACR Meeting, 2009 [.pdf]